The 33-year-old Brazilian midfielder is out of contract in July and his departure was announced on Thursday.

Casemiro out of Brazil squad with injury, Porto forward Pepe to take his place

The 24-year-old defender has been injured since August.

Casemiro, on his return from injury, was replaced at half-time of the 3-0 defeat and United have now confirmed he will miss a key run of fixtures.